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A typical CoA of Antazoline Hydrochloride and Antazoline Phosphate is given below, please contact topharman@topharman.com for more quality items of Antazoline Hydrochloride and Antazoline Phosphate.
| Product Name: Antazoline Hydrochloride |
Quantity: 1kg |
CAS Registry Number: 2508-72-7
|
Lot No.: Typical |
| Molecular Formula: C17H20ClN3 |
Molecular Weight: 301.8 |
| Structure |
 |
| Item |
Requirement |
Result |
| Description |
White or almost white crystalline powder |
Almost white crystalline powder |
| Solubility |
Sparingly soluble in water,
soluble in alcohol, slightly
soluble in methylene chloride |
Comply |
| Identification |
i, IR; ii, TLC; iii, It gives reaction of chlorides |
Comply |
| Melting Point |
It melts at about 240℃,with decomposition |
237.2-239.3℃,
with decomposition |
| Appearance of Solution |
As per BP |
Comply |
| Acidity or Alkalinity |
As per BP |
Comply |
| Heavy Metals |
Less than 20ppm |
Comply |
| Loss on Drying |
Not more than 0.5% |
0.07% |
| Residue on Ignition |
Not more than 0.1% |
0.04% |
| Related Substances |
TLC test should pass as per BP |
Comply |
| Assay (on the dried basis) |
99.0%~101.0% |
99.81% |
| Conclusion: |
Complies with requirements of BP2002, ANTA-HCl |
| Product Name: Antazoline Phosphate |
Quantity: 1kg |
CAS Registry Number: 154-68-7
|
Lot No.: Typical |
| Molecular Formula: C17H19N3•H3PO4 |
Molecular Weight: 363.35 |
| Structure |
 |
| Item |
Requirement |
Result |
| Description |
White to off-white, crystalline powder, having a bitter taste |
Off white crystalline
powder, having a bitter taste |
| Solubility |
Soluble in water; sparingly soluble in methanol; practically insoluble in benzene and in ether |
Comply |
| Identification |
i, IR; ii, TLC |
Comply |
| Melting Point |
194~198℃, with decomposition |
193-195℃,with decomposition |
| pH |
4.0~5.0, in a solution (1 in 50) |
4.48 |
| Loss on Drying |
≤0.5% |
0.08% |
| Assay (on the dried basis) |
98.0%~101.0% |
99.94% |
| Purity (HPLC) |
≥99% |
99.84% |
| Impurities (HPLC) |
Individual: ≤0.5% Total: ≤1.0%
|
Individual:0.07% Total:0.16%
|
| Conclusion: |
Complies with requirements of USP27, ANTA-P |
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